Scientists from US and China have developed a new adhesive patch that could reduce the stretching of cardiac muscle following a heart attack.
Developed by a team of researchers from Brown University, US; Fudan University, China and Soochow University, China, the patch is made from a water-based hydrogel material and can be placed directly on the heart to prevent left ventricular remodelling, a stretching of the heart muscle.
A heart attack puts the cardiac muscle at a risk of stretching out that can reduce the functioning of the heart’s main pumping chamber. it’s hard for the heart to recover after a heart attack is that it has to keep pumping.
The researchers said the patch, which costs “less than a penny”, has been optimised using a computer model of the heart to perfectly match the material’s mechanical properties.
For the research, published in Nature Biomedical Engineering, the team tested the patch and showed that the patch could be effective in reducing post-heart attack damage.
The patch provided nearly optimal mechanical supports after myocardial infarction i.e. massive death of cardiomyocytes.
It maintained a better cardiac output and thus greatly reduced the overload of those remaining cardiomyocytes and adverse cardiac remodelling. The researchers say the initial results are promising for eventual use in human clinical trials.
FROM AWARD-WINNING AUTHOR DR GOVIND SHUKLA, NUTRITION EXPERT
Govind Shukla, Specializes in Pharmacology, Toxicology, Nutraceuticals & Herbal Drugs has published More than 100 research papers in National & International Journals. He is also a reviewer of International Journal of Pharmacology & pharmacotherapeutics, Chief editor of IJPNR Journal & Freelance Medical Writer for Different publication Groups including Lambert Academic Publishing Saarbrucken, Germany.